Fibroblast growth factor sterile
Basic fibroblast growth factor; basic FGF; FGF-2; FGF-b
The main fibroblast growth factor has mitogenic activity and affects cell survival. FGF factors are involved in various biological processes, including embryonic development, cell growth, morphogenesis, tissue repair and tumor growth. FGF modifies migration of endothelial cells and acts as an angiogenic factor. It is a mitogenic factor for mesodermal and neuroectodermal cells in vitro, thus FGF-2 is involved in organogenesis. Due to alternative splicing, different isoforms are described. Heparin-bound protein in vivo is an angiogenic factor and a mitogenic factor for many cell types in vitro.
This product is intended for research purposes.
Human recombinant FGF-2 is produced by E. coli. It consists of 154 amino acid residues.
Molecular weight is 17.2 kDa.
Lyophilized from sterile 20 mM Tris-HCl, pH 7.4 and 1M NaC.
The purity was determined by electrophoresis in polyacrylamide gel and is 98%.
The dry preparation is stable at room temperature for 3 weeks, longer storage is permissible at -18℃.
The diluted solution should be stored at temperature of 4℃ for 2-7 days, for longer storage use carrier protein (0.1% BSA) and freezing -18℃.
Do not allow repeated freezing and thawing cycles.