Bovine insulin
Insulin from bovine pancreas.
Insulin regulates absorption, storage and utilization of glucose, amino acids and fatty acids. It inhibits breakdown of glycogen, proteins and fats.
Bovine insulin is used as growth factor in cultivation of a wide range of mammalian cells. Bovine insulin is used to differentiate mesenchymal stem cells (MSCs) into adipocytes. And also in the study of insulin-mediated inhibition of the HMGCS2 gene (3-hydroxy-3-methylglutaryl-coenzyme A synthase).
Bovine insulin is a hormone that has the form of a double-stranded polypeptide chain. It is produced by β-cells of pancreatic islets. Molecular weight is 5.8 kDa, α and β chains are connected by two inter-chain disulfide bonds. There is an intra-chain disulfide bridge in α chain.
This product is intended for research purposes.
- Appearance: white powder. The solution is colorless, clear.
- pH: 10 ±0,5
PREPARATION INSTRUCTIONS: Insulin is poorly soluble at neutral pH. Dilution of 2 mg/ml is possible in solution of acetic or hydrochloric acid at pH of 2-3.
HOW SUPPLIED: in sterile glass bottle of 10 ml.
SHELF LIFE: 1 year.
STORAGE: -20 °C in a place protected from light.
Store insulin solution at temperature of +2 to +8 oC. Do not freeze the solution. Sterile solution is stable when stored in the refrigerator for 1 year.
RECOMMENDED USE:
- Do not use the product after its expiry date.
- Use gloves, mask and clothes adapted to the manipulation of the product to avoid contamination.
- Manipulate the product in aseptic conditions.
