Insulin from bovine pancreas
This product is intended for research purposes.
Insulin regulates absorption, storage and utilization of glucose, amino acids and fatty acids. It inhibits breakdown of glycogen, proteins and fats.
Bovine insulin is used as growth factor in cultivation of a wide range of mammalian cells. Bovine insulin is used to differentiate mesenchymal stem cells (MSCs) into adipocytes. And also in the study of insulin-mediated inhibition of the HMGCS2 gene (3-hydroxy-3-methylglutaryl-coenzyme A synthase).
Bovine insulin is a hormone that has the form of a double-stranded polypeptide chain. It is produced by β-cells of pancreatic islets. Molecular weight is 5.8 kDa, α and β chains are connected by two inter-chain disulfide bonds. There is an intra-chain disulfide bridge in α chain.
The preparation is white powder. The solution is colorless, clear.
Store at temperature of -20 ° C.
Recommendations for breeding. Insulin is poorly soluble at neutral pH. Dilution of 2 mg / ml is possible in solution of acetic or hydrochloric acid at pH of 2-3.
Store insulin solution at temperature of +2 to +8 oC. Do not freeze the solution. Sterile solution is stable when stored in the refrigerator for 1 year.