Collagenase (type 4) sterile, lyophilized
Collagenase is an enzyme cleaves the peptide bonds between neutral amino acids (X) and glycine in amino acid sequence Pro-X-Gli-Pro. This sequence is often found in collagen. Collagenase is unique proteases. It has ability to break down collagen fibrils which has found in all types of connective tissue, such as skin, bones, tendons, blood vessels.
The ability of collagenase to destroy collagen is used in culture of human tumor cells, mouse kidney cells, brain nerve cells and many other cells except for epithelial ones. The effect on cells is rather mild, collagenase works at physiological temperature and pH, has no mechanical effect, and also does not require special equipment.
Type 4 collagenase is specific for separation and isolation of pancreatic islet cells. Sterile powder, used for research purposes for splitting tissues into individual cells.
Collagenase was lyophilized from Clostridium histolyticum culture.
Avoid inhalation and skin contact!
This product is intended for research purposes.
- Enzyme content is not less than 125 EU/mg.
SHELF LIFE: 1 year.
STORAGE CONDITIONS: +2 to +8 °C in a place protected from light.
RECOMMENDED USE:
- Do not use the product after its expiry date.
- Use gloves, mask and clothes adapted to the manipulation of the product to avoid contamination.
- Manipulate the product in aseptic conditions.
